CMC Project Manager – Antibody-Drug Conjugates (ADCs)

Location: Germany (Hybrid)

About the Company

Our client is an innovative biotechnology company developing next-generation targeted therapeutics and antibody-drug conjugates (ADCs) for the treatment of cancer. With proprietary technology platforms and multiple programs already in clinical development, the company is redefining how precision oncology medicines are designed and delivered. Their mission is to create safer, more effective therapies that make a meaningful impact for patients worldwide.

The Role

They’re seeking a proactive and experienced CMC Project Manager to oversee CMC development and supply chain activities for an advancing ADC portfolio. You’ll coordinate cross-functional efforts across process development, GMP manufacturing, and late-stage development, ensuring CMC programs are delivered on time, within budget, and aligned with clinical milestones.

The role reports into the SVP of CMC and works closely with internal CMC leads, Program Management, Finance, and Clinical Operations teams, as well as external CMOs and partners.

Key Responsibilities

• Manage CMC and supply chain activities for programs transitioning into GMP and late-stage development.
• Develop comprehensive CMC project plans covering scope, goals, timelines, and dependencies.
• Implement project strategies that ensure delivery against development milestones.
• Coordinate cross-functional project teams and external manufacturing partners, maintaining agendas, minutes, and follow-up actions.
• Track CMC program budgets, reconcile invoices, and manage resources efficiently.
• Identify and mitigate project risks with CMC and Regulatory leads.
• Maintain clear and regular communication with stakeholders, providing status updates and progress reports.
• Support leadership with project tracking, dashboards, and decision-making tools.

Requirements

• Master’s degree or higher in Chemistry, Biotechnology, Biochemistry, or related discipline.
• 8+ years’ CMC experience within pharma, biotech, or related sectors.
• 5+ years’ experience in project management, ideally including late-stage development.
• Strong understanding of biopharmaceutical product lifecycles (pre-IND through commercial), GMP manufacturing, and CMC process development.
• Familiarity with FDA/EMA CMC regulations and quality standards.
• Demonstrated success leading cross-functional teams and managing external partners.
• Excellent communication, stakeholder, and presentation skills.
• Proficiency in project management tools (e.g. MS Project, Excel, PowerPoint).
• Fluent in English (written and spoken).
• Self-motivated, highly organised, and comfortable working in fast-paced environments.

What’s on Offer

• Flat hierarchies and short decision-making lines.
• Hybrid working with a supportive, collaborative culture.
• 30 days’ vacation and a permanent contract after probation.
• Mobility allowance and modern office facilities.
• A strong sense of team spirit, inclusion, and scientific excellence.