Senior Scientist, Pharmacology

Posted 29 September 2022
LocationWatertown
Job type Permanent
Reference68535
Contact NameKayleigh Best

Job description

Senior Scientist, Pharmacology ~ MA

 

BioTalent are partnered with an early-stage, VC-backed oncology biotherapeutics start-up who are looking for a Senior Scientist to join their Pharmacology team.

 

In this position, you will:

  • Design, plan and execute syngeneic murine pharmacology studies independently, focusing on anti-tumor activity, PK/PD relationship, MOA and biomarker identification.
  • Perform studies using an external CRO/mouse vivarium
  • Analyze various mouse, NHP plasma, and tumor samples to answer PK, PD, MOA, and biomarker questions
  • Use various cell-based/biochemical assays for sample analysis, including ELISA, AlphaLISA, Luminex, Jess (Proteinsimple) protein analysis, cell-based activity, proliferation assays, and various others.
  • Advise the translational team on the use and selection of various syngeneic mouse models
  • Use external CRO resources to develop external histopathology and gene expression assays.
  • Perform statistical analysis of experimental data from in vitro and in vivo studies.

 

Preferred Qualifications include:

  • Ph.D. in Cell, Molecular or Cancer Biology, Pharmacology, or related discipline
  • 3+ years of experience (industrial or postdoctoral) in a cancer, immunology or bioanalytical laboratory
  • Extensive hands-on experience with mouse syngeneic tumor models and PK/PD studies, alongside strong expertise in cellular tumor immunology, immune checkpoints and T cell/NK biology is a plus

 

Please apply to this posting or reach out to kayleigh.best@biotalent.com for a confidential conversation to learn more!