Research Scientist HDX, Structural, Native Mass Spectrometry

Posted 18 October 2022
Job type Permanent
DisciplineResearch & Development
Contact NameLewis Besbeech

Job description

We are extremely excited to be working with a unique, tenacious and forward-thinking biopharmaceutical company based in Oxford, UK.

Together we are looking for a professional who is innovative, a natural problem solver and has a desire for pushing boundaries in their work, you will need experience with developing methods or approaches in hydrogen deuterium exchange (HDX), native mass spectrometry (MS), structural / mechanistic MS or experience using MS to understand small molecule interactions.

This role will offer you:

  • An inclusive company culture engaged with creating transformative medicines.
  • A non-discriminatory, equal opportunity employer that you can be proud to work for.
  • A chance to work at the interface of chemistry, cellular biology, structural biology and biophysics.


You will be responsible for:

  • Developing, optimising and executing structural MS experiments.
  • Recording and analysing complex data, synthesising outcomes into conclusions / recommendations.
  • Carrying out experimental troubleshooting.
  • Being aware of emerging technologies that can advance existing technology platforms.
  • Preparation and presentation of experimental findings to internal department or project team meetings.
  • Contributing to patent and/or publication preparation.


You will bring the following:

  • Practical experience with HDX or structural MS.
  • Experience with native MS for characterisation of proteins, nucleotides, biotherapeutics or ligand interactions.
  • A strong team mentality, with the ability to work at the interface of multiple disciplines.
  • Excellent communicative and time management skills.


Contact details below are there if you would like to learn more about this exciting opportunity!



Telephone: +44 (0)2037289989


BioTalent Ltd are acting as an employment agency in relation to this opportunity.