Medicinal Chemistry Scale-up Senior Research Scientist

Posted 11 November 2022
Job type Permanent
DisciplineResearch & Development
Contact NameLewis Besbeech

Job description

This extremely refreshing opportunity will be working with one of my world class equal opportunity pharmaceutical employers, they host a fearless, forward-thinking approach within their med chem team and across the business and together we are searching for an innovative, dynamic Medicinal Chemistry leader.


The Medicinal Chemistry Scale-up Senior Research Scientist will be responsible for experimental productivity and the streamlining of scale-up procedures. You will work as part of a high performing med chem scale-up team and be expected to conduct independent synthesis of compounds and intermediates on a range of scales from multi grams to hundreds of grams. Additionally, you will be expected to carry out complex experimental procedures, method development and troubleshooting.


This role will offer you:

  • A positive and rewarding working environment centred within a modernised facility.
  • Freedom to design, develop and optimise processes to your own style of working.
  • Influence in project decisions and new research activities.


You will be responsible for:

  • Designing and conducting synthetic experiments (working on a range of scales to produce 10s grams to 100s grams of final APIs) and other challenging chemistry experiments.
  • Delivering material and develop/optimise processes independently.
  • Collaborating with your high performing Scale-up team to achieve rapid material delivery and contribute/lead problem solving activities.
  • Gathering and analysing complex data, synthesising results into conclusions/recommendations to influence project decisions and new research tasks.
  • Carrying out advanced and/or complex experimental troubleshooting.
  • Highlighting and introducing relevant emerging technologies in your specialised field to advance existing technology platforms.
  • Making significant contribution to patent and/or publication preparation.
  • Preparing study presentations and delivering experimental conclusions.
  • Performs other duties as assigned.


You will bring the following:

  • Experience working in a large-scale, synthetic laboratory delivering complex organic compounds.
  • Experience with using large-scale glassware 5L to 30L.
  • Experience and understanding of process safety and hazard assessments.
  • Strong synthetic knowledge and understanding.
  • Experience designing and executing complex, challenging experiments.
  • Desirable - Ph.D. (or equivalent) in chemistry or related science and relevant post-doctoral employment experience.
  • Accepting - Masters or Bachelors degree (or equivalent) in chemistry or related science with relevant employment experience.


Please use the contact details below if you would like to learn more about this exciting opportunity!


Telephone: +44 (0)2033438780 or +44 (0)2037289989

BioTalent Ltd are acting as an employment agency in relation to this opportunity.